Treating Alzheimer’s patients with TPS: TPS reduces cortical atrophy in Alzheimer’s

The authors of a follow-up study (published in 2021) investigated the possible benefits of TPS® treatment concerning brain morphology, namely the cortical atrophy characteristic of Alzheimer’s disease [1]. They found a significant correlation between neuropsychological improvement and cortical thickness increase in AD-critical brain areas.

AD patients who benefit from TPS® appear to manifest reduced cortical atrophy within the default mode network in particular, whose memory-related subsystems are believed to be disrupted in AD. This was found for the left precuneus and the superior parietal lobule.

 [1] Popescu T, Pernet C, Beisteiner R. Transcranial ultrasound pulse stimulation reduces cortical atrophy in Alzheimer’s patients: A follow-up study. Alzheimer’s Dement. 2021;7:e12121. https://doi.org/10.1002/trc2.12121
(Read the full paper here: https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/trc2.12121)