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On this page, people with Alzheimer's dementia and their families will find the latest information about Transcranial Pulse Stimulation (TPS) with the NEUROLITH® system.
What's new in TPS research and how do experts assess the non-invasive procedure? How does TPS work and how is it used in addition to standard therapy? What do patients say about the treatment? Read the latest articles now and deepen your knowledge.
Transcranial Pulse Stimulation (TPS) is an innovative treatment method for patients with Alzheimer’s disease. To better understand its clinical application and gain an overview of patient numbers and treatment outcomes, we conduct annual surveys. This year’s survey included participation from 33 centres. The analysis provides valuable insights into the practical use of TPS in patients with Alzheimer’s disease.
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Current state of research and perspectives for patients
The treatment of neurodegenerative diseases poses major challenges for patients, their families, and the medical community. In addition to pharmacological therapies, non-invasive, complementary approaches are therefore gaining increasing importance. One of these approaches is Transcranial Pulse Stimulation (TPS), which has already been used in patients with Alzheimer’s disease.
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Transcranial Pulse Stimulation (TPS) continues to advance as a promising non-invasive neuromodulation technique in neuroscience. With growing evidence of therapeutic benefits in Alzheimer’s disease — including improvements in memory, mood, and cognition — research is increasingly focused on uncovering the underlying mechanisms of TPS.
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Parkinson's disease is not only the second most prevalent neurodegenerative disease after Alzheimer's disease, but also the fastest growing. With the number of cases steadily increasing, there is an urgent need for innovative therapeutic approaches.
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Alzheimer’s disease (AD) continues to pose one of the greatest challenges in medicine, with progressive cognitive decline and limited treatment options. A recently published study by Cont et al., under the lead of Prof. Lars Wojtecki, explores the potential of Transcranial Pulse Stimulation (TPS) as an add-on treatment for AD. The research was carried out by the team at the Department of Neurology and Neurorehabilitation at the Hospital zum Heiligen Geist in Kempen, Germany, together with the Institute of Clinical Neuroscience and Medical Psychology at Heinrich-Heine University Düsseldorf. By evaluating the feasibility, safety, and cognitive effects of TPS over a full year, this work provides valuable long-term data on its use in patients with Alzheimer’s disease.
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The newly released video publication on Transcranial Pulse Stimulation (TPS) for patients with Alzheimer’s disease by Cont et al., led by TPS expert and key opinion leader Prof. Lars Wojtecki, has recently been published by »Journal of Visualized Experiments (JoVE)« in the Neuroscience section. This innovative format combines hands-on methodology with scientific context, offering a practical demonstration of the TPS treatment protocol alongside a concise overview of the most representative clinical data published to date. The key message: TPS provides several distinct advantages and holds strong potential as a complementary therapeutic option for patients with Alzheimer’s disease.
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Alzheimer’s disease (AD) is clinically characterized by progressive cognitive decline, affecting memory, language, orientation, and behaviour. Neural oscillations, also known as brain waves, are integral to cognitive processes but become dysregulated in AD, contributing to network dysfunction and memory impairments. Targeting these oscillations has emerged as a promising therapeutic strategy. A new review article summarizes key findings from studies on neural oscillations as therapeutic targets in AD and discusses various invasive and non-invasive brain stimulation techniques – including Transcranial Pulse Stimulation (TPS).1
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A new milestone in TPS research for Alzheimer’s has been achieved! For the first time, scientists have conducted a detailed animal study on healthy and transgenic mice with Alzheimer’s to explore the effects of Transcranial Pulse Stimulation (TPS). This study, a collaborative effort between ETH Zurich and University of Zurich, funded by InnoSuisse, investigated how TPS influences both brain structure and blood flow. The results, published in the prestigious journal Alzheimer & Dementia, are exciting: not only did TPS improve microcirculation in the brain, but it also demonstrated a high level of safety by maintaining the integrity of the blood-brain barrier (BBB) even at higher energy levels.
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Alzheimer's disease is a challenging condition that affects millions of people worldwide. It gradually impairs memory, thinking, and other mental abilities, making everyday life difficult for those affected and their loved ones. While there are treatments that help manage the symptoms, scientists are constantly searching for new ways to improve brain function in Alzheimer's patients. One promising approach is a treatment called Transcranial Pulse Stimulation, or TPS.
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Wondering how Transcranial Pulse Stimulation (TPS) could help treat Alzheimer’s disease? In this video, you will find an explanation of Prof. Lars Wojtecki’s study that investigates the safety and effectiveness of TPS, an innovative brain stimulation technique, for patients with mild to severe Alzheimer’s.
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Transcranial Pulse Stimulation (TPS) is an innovative treatment method for patients with Alzheimer's dementia. To better understand its application, obtain an overview of patient numbers and gain a clinical global impression of the treatment outcomes, we conduct annual surveys. In this year's survey, 35 centres participated. In this blog post, you can discover the latest findings and analyses from our recent TPS survey.
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Neurological disorders, encompassing a wide spectrum from neurodevelopmental conditions to late-life neurodegeneration, represent a significant global health challenge. The Global Burden of Disease Study 20211, published in The Lancet Neurology 2024, offers a comprehensive insight into the impact of 37 neurological conditions worldwide, marking a significant step forward in understanding the full scope of neurological disorders, including Alzheimer's disease.
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