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On this page, people with Alzheimer's dementia and their families will find the latest information about Transcranial Pulse Stimulation (TPS) with the NEUROLITH® system.
What's new in TPS research and how do experts assess the non-invasive procedure? How does TPS work and how is it used in addition to standard therapy? What do patients say about the treatment? Read the latest articles now and deepen your knowledge.
A study by Matt et al. (Medical University of Vienna, University Department of Neurology) published in January 2022 investigates the long-term effects of Transcranial Pulse Stimulation (TPS) with the NEUROLITH® system on human brain and behaviour.1 The randomised, sham-controlled and double-blinded study provides sham-controlled evidence for such effects for the first time.
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Transcranial Pulse Stimulation (TPS) celebrates its debut in Ukraine: The first NEUROLITH® system was installed in the western Ukrainian city and cultural centre of Lviv (approx. 750,000 inhabitants) on 12 January 2022. Now, Alzheimer's patients can receive treatment at »BRAINSPOT LVIV«, a clinic for neuromodulation (Director: Tomas Dzeminskyy, Chief Medical Officer: Andrii Hul). The first therapy sessions have already taken place.
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In early January 2022, a study on the development of global dementia prevalence published by the medical journal The Lancet Public Health1 received a lot of attention. The study predicts that the number of cases will triple to 152.8 million by 2050.The World Alzheimer Report 2019 already came to a similar assessment. The most important factors for this explosive development are the ageing of the global population and its further growth.
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It's getting exciting: In the RTL News report »Neue Alzheimer-Therapie: Sanfte Stosswellen bringen Gedächtnis zurück«. Prof. Dr Musa Citak introduces in his practice in Hamburg the NEUROLITH® system and the treatment method, Transcranial Pulse Stimulation – short TPS.
TPS as a modern therapy method for the treatment of Alzheimer's dementia stimulates different brain regions even in deeper areas.
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Transcranial Pulse Stimulation (TPS) with the NEUROLITH® system is a new therapy option for patients with Alzheimer’s disease that allows targeted stimulation of cerebral regions.
Key-facts:
- TPS are shock waves which allow highly focal brain stimulation deep in the brain.
- TPS allows unprecedented precision for targeting brain areas.
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Transcranial Pulse Stimulation (TPS) with the NEUROLITH® is increasingly gaining momentum: Since the CE approval for the »treatment of the central nervous system of patients with Alzheimer’s disease« in 2018, more than 50 NEUROLITH® systems have been installed worldwide. In June 2021, three more devices were installed in renowned neurological specialist clinics in Germany, Austria, and Turkey.
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One of the highlights of the new NEUROLITH® system is its innovative BodyTrack software – a unique tool for the visualization and control of the TPS pulses applied and of treatment progress. Real-time tracking of the handpiece position enables automatic visualization of the treated regions. The use of personalized MRI data allows specific characteristics of the patient’s brain to be taken into account.
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»Overall, I feel good after the treatment and progress has been made. I notice that I respond well when someone talks to me and find the words to express myself better. In addition, my memory has improved somewhat. When I go shopping, I take the shopping list just to be on the safe side, although I could do without it.
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Transcranial Pulse Stimulation (TPS) with the NEUROLITH® system is performed by a trained practitioner and is done on an outpatient basis. During treatment, the patient sits comfortably in a chair and can move freely at any time. To ensure optimal transmission of the pulses, the therapist applies ultrasound gel to the scalp or hair – it is not necessary to shave the patient’s head. The patient then puts on a pair of special glasses so that the position of the head can be detected.
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The authors of a follow-up study (published in 2021) investigated the possible benefits of TPS treatment concerning brain morphology, namely the cortical atrophy characteristic of Alzheimer’s disease [1]. They found a significant correlation between neuropsychological improvement and cortical thickness increase in AD-critical brain areas.
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»Laughing and being happy - for healthy people this is normal. During my TPS treatments, I notice that this is no longer normal for my patients. Many are sad and seem withdrawn. This is understandable when you can no longer do things the way you used to. I am all the more pleased when relatives call me after the first TPS treatments with the NEUROLITH® or write to me that their loved ones are now happier again and that they are smiling more often.
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In 2019, the clinical approval study for Transcranial Pulse Stimulation (TPS) with STORZ MEDICAL’s NEUROLITH® system was published in the prestigious journal Advanced Science [1]. Prof. Dr. Beisteiner’s study, which was conducted at the Medical University of Vienna Beisteiner, documents the positive effects of TPS in the treatment of patients with Alzheimer’s dementia.
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